The bioconcentration factor bcf for cyclohexanone can be estimated to be 2. The cyclohexanone is extracted into methylene chloride. Potassium carbonate anhydrous certified acs revision date 18sep2018 disclaimer the information provided in this safety data sheet is correct to the best of our knowledge, information and belief at the date of its publication. If inhaled if breathed in, move person into fresh air. Eyes if material gets into eyes or if fumes cause irritation, immediately flush eyes with plenty of water until chemical is removed. Buy cyclohexanone leading chemical suppliers reagent. It is an important building block for the synthesis of a variety of organic compounds. Make sure to discuss and label the oh stretch and the co stretch on the cyclohexanol spectrum. One of the methods reported for its synthesis is by the palladium catalyzed hydrogenation of phenol. First aid measures general advice move out of dangerous area. Sigmaaldrich c102180 page 1 of 6 sigmaaldrich material safety data sheet version 4. Follow the osha respirator regulations found in 29 cfr 1910. This material does not contain any hazardous air pollutants.
To salt out the cyclohexanone, add to the distillate 0. Dry powders can build static electricity charges when subjected to the friction of transfer and mixing operations. Potassium nitrate safety data sheet according to federal register vol. Always wear recommended personal protective equipment. Online edition for students of organic chemistry lab. Cyclohexanone 2,4dinitrophenylhydrazone santa cruz. Over time, samples of cyclohexanone assume a yellow color. Cyclohexanone, a colorless liquid is a cyclic ketone. A blank cell indicates the fabric has not been tested.
The following list contains the material safety data sheets you requested. Collect contaminated fire extinguishing water separately. Page 4 of 8 msds t benzyl alcohol lightresistant containers. Cyclohexanone is readily biodegradable according to aerobic screening tests and. Cyclohexanone ld50 1544 mgkg rat ld50 947 mgkg rabbit lc50 8000 ppm rat 4 h toxicologically synergistic products no information available delayed and immediate effects as well as chronic effects from short and longterm exposure irritation causes eye burns. The information given is designed only as a guidance for safe handling, use, processing, storage.
The information in cameo chemicals comes from a variety of data sources. Cyclohexanone is the organic compound with the formula ch 2 5 co. Material safety data sheet cyclohexane msds number. Not classifiable as to its carcinogenicity to humans cyclohexanone reproductive toxicity overexposure may cause reproductive disorders bas ed on tests with laboratory animals.
Cyclohexanone is slightly soluble in water and miscible with common. Use of the information, documents and data from the echa website is subject to the terms and conditions of this legal notice, and subject to other binding limitations provided for under applicable law, the information, documents and data made available on the echa website may be reproduced, distributed andor used, totally or in part, for noncommercial purposes provided that echa is. India veritas house, 70 mint road, fort, mumbai 400 001. This colorless oil has an odor reminiscent of that of acetone. Ensure all equipment is electrically grounded before beginning transfer operations. Safety data sheet cyclohexanone hill brothers chemical. May cause symptoms listed under inhalation, dizziness, fatigue, tremors, permanent central nervous system. Carefully add cyclohexanone, drop wise, to the small test tube until the balance shows a mass of 0. If irritation persists, get medical attention immediately.
The following list contains the material safety data sheets. Jun 06, 2018 the synthesis of cyclohexanone is a simple procedure that uses acetic acid, sodium hypochlorite, hypochlorous acid, ether, sodium chloride, sodium carbonate and cyclohexanol. Cyclohexanone material safety data sheet cas no 108941. Chemtrec 8004249300 outside usa 7035273887 1216 6th ave n kent wa 98032 phone. Sigmaaldrich 3050 spruce street saint louis mo 63103 usa. Iarc no component of this product present at levels greater than or equal to 0. Wear appropriate protective clothing to prevent skin exposure. Specific target organ toxicity single exposure no data available acute inhalation toxicity breathing difficulties. Aug 03, 2009 the molar mass of cyclohexanone is 98. Material safety data sheet cyclohexanone msds section 1. Potassium permanganate safety data sheet according to federal register vol. Dissolving inorganic salts such as potassium carbonate or sodium chloride in the aqueous layer will decrease the solubility of cyclohexanone such that it can be completely extracted with ether. P210 keep away from heat, sparks, open flames, hot surfaces. If medical advice is needed, have product container or label at hand keep out of reach of children read label.
Irritating to skin sensitization no information available. Safety data sheet creation date 14sep2009 revision date 29oct2018 revision number 4 1. Safety data sheet cyclohexanone hill brothers chemical co. Print pdf page for determination of zinc by the zincon zincover 5 method. Cyclohexanone is readily biodegradable according to aerobic screening tests and therefore would be expected to biodegrade in soil.
Uses advised against food, drug, pesticide or biocidal product use details of the supplier of the safety data sheet. The synthesis is done by simply adding the acetic acid and sodium hypochlorite, which is also known as hypochlorous acid to. Majority of the cyclohexanone synthesized is utilized as an intermediate in the synthesis of nylon. Provide exhaust ventilation or other engineering controls t o keep the airborne concentrations of vapors below their respective threshold limit value. Page 6 of 8 msds t benzyl alcohol special remarks on other toxic effects on humans. In view of its moderate vapor pressure and low adsorption to soil, it would be expected to volatilize from surface soil. These intermediates are important in the manufacture of nylon6 and. The mixture was cooled to 0c with an ice bath and pyrrolidine 1. The hazard fields include special hazard alerts air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents. This material does not contain any class 1 ozone depletors.
With larger ingestions there is potential for systemic t oxicity from gastrointestinal absorption and decontamination is suggested, keeping in mind that aspirat ion is still a concern. Sds of cyclohexanone, safety data sheets, cas 108941. Potassium iodide revision date 29oct2018 y2 indicates an exempt polymer that is a polyester and is made only from reactants included in a specified list of low concern reactants that comprises one of the eligibility criteria for the exemption rule. Show this safety data sheet to the doctor in attendance. The co stretch on the cyclohexanone spectrum and show the absence of the alcohol stretches. Although data are lacking, it may also undergo direct photolysis on the soil surface. Place a glass thermometer into the beaker and measure the temperature of the mixture. Buy your topgrade cyclohexanone online from reagent, a leading uk chemical supplier with over 40 years experience. It is a colorless, oily liquid with an acetone like smell.
It may be absorbed through the skin with symp toms similar to that of ingestion. The molecule consists of sixcarbon cyclic molecule with a ketone functional group. Safety data sheet according to 29cfr19101200 and ghs rev. Identification of the substancemixture and of the companyundertaking 1. Exposure controlspersonal protection engineering controls. Cyclohexanone also known as oxocyclohexane, pimelic ketone, ketohexamethylene, cyclohexyl ketone or ketocyclohexane is a six carbon cyclic molecule with a ketone functional group. Compare and contrast your ftir versus the literature ir for the starting material and the product see below. Fire residues and contaminated fire extinguishing water must be disposed of in accordance with local regulations. A novel process for preparing cyclohexanone derivatives of formula i is described. The products are useful as gamma secretase inhibitors, or as intermediates in the synthesis of other gamma secretase inhibitors. On a balance, tare a small test tube that has been placed in an empty 50 to 100ml beaker for stabilization. Identification product name potassium iodide cat no.